4T1-Luc2 (CRL-2539-LUC2)

Mammary tumor cell line (luciferase-expressing)

4T1-Luc2 cells are a luciferase-expressing cell line derived from parental line CRL-2539 by transduction with lentiviral vector encoding firefly luciferase gene (luc2) under control of EF-1 alpha promoter. Excellent signal/background ratio and stable Luciferase expression make this cell line ideal for in vivo bioluminescence imaging of xenograft animal model to study human cancer and monitor activity of anti-cancer drug. It also can be used in cell-based assays for cancer research.

Product category:
Animal cells
Product type:
Cell model Reporter-labeled cell
Disease:
Mimics human breast cancer Stage IV
Organism:
Mus musculus, mouse
Product format:
Frozen
Morphology:
epithelial-like
Storage conditions:
Vapor phase of liquid nitrogen
Tissue:
Breast Mammary gland
Applications:
3D cell culture, Assay development
Cancer research, High-throughput screening

RAW 264.7 (TIB-71)

Murine macrophage cell line

RAW 264.7 is an adherent cell line isolated from a mouse tumor that was induced by Abelson murine leukemia virus. This cell line, with macrophage differentiation, can be used in oxidative stress, inflammatory, and antibacterial activity studies. RAW 264.7 is tumorigenic and is widely used in cancer and drug development research.

Product category:
Animal cells
Tissue:
Ascites
Disease:
Abelson murine leukemia virus-induced tumor
Cell type:
macrophage
Organism:
Mus musculus, mouse
Product format:
Frozen
Morphology:
monocyte/macrophage
Storage conditions:
Vapor phase of liquid nitrogen
Applications:
3D cell culture
Immune system disorder research
Immunology

IC-21 (TIB-186)

Peritoneal macrophage cell line

IC-21 is a macrophage cell that was isolated from a mouse and can be used in immunology.

Product category:
Animal cells
Cell type:
macrophage
Organism:
Mus musculus, mouse
Applications:
3D cell culture Immunology
Product format:
Frozen
Classification:
Eukaryota, Animalia, Metazoa
Chordata, Vertebrata, Tetrapod